Molecular imaging enables the search for a different kind of discovery. The kind that has the ability to have a lasting impact on the world. A true discovery. Not only is it proof of a new way to understand something hidden deep within us, it has the ability to transcend the individual to make a greater impact on all patients.

CZT is the key component to the future of nuclear medicine. Not only is it lighter and more compact than the Nal crystals used in analog technology, it is pixelated. Housed within smaller and sleeker 39 cm x 51 cm FOV Planar and SPECT detector heads, each individual detector is like the eye of a fly, with thousands of tiny 2.46 mm sized detectors working together to capture more events, more accurately. It also enables direct conversion. With CZT, each photon is directly converted into an electrical signal that accurately identifies its location and energy. This eliminates the signal loss and noise inherent in conventional SPECT/CT detection technology, recovering lost spatial and energy resolution.

Discovery NM/CT 670 CZT is the first general purpose system designed with this breakthrough detection technology. Combined with registered collimation to deliver higher resolution images, edge-to-edge performance allowing for more comfortable positioning of your patients and the latest in advanced quantitative applications provided by Xeleris, this system is capable of transforming the entire nuclear medicine experience.

THE FUTURE OF NUCLEAR MEDICINE IS HERE

As molecular imaging continues to move toward the development of disease specific diagnoses and increasingly personalized care, clinicians are looking for technology that will get them there. For nuclear medicine, resolution is important. Early disease detection is only possible with a high system resolution that enables visualization of finer anatomic detail. In addition, research with multi-isotope exams requires precise energy resolution to reduce spillover between tracers.

With direct conversion detection, Discovery NM/CT 670 CZT has substantially improved system resolution by eliminating the signal loss and noise that comes with analog detection technology. It also uses a registered collimation design that aligns each collimator with a single detector pixel. This design eliminates the impact of collimator resolution that would normally effect the overall system resolution. The result is an improved contrast-to-noise ratio and spatial resolution down to 2.8 mm.

CZT can also simultaneously detect the energy from multiple tracers with more definition than conventional technology. Its 6.3 percent energy resolution makes it possible to explore new protocols with the variety of SPECT tracers available.

SEE EVERYTHING CLEARLY NOW

Often times, the technology needed to produce a specific result has an impact on the overall experience of getting that result. Many consumer industries have had to work around the design constraints that come with analog technology. For nuclear medicine, the crystal and photomultiplier tubes have to overlap beyond the useful field of view in order to limit image degradation at the edges. This creates a significant amount of unusable dead space at the edge of the detector making some procedures difficult, at times impossible, for patients to physically endure.

With a patient-centric design, certain exams become tolerable. One such exam is a cardiac SPECT scan requiring patients to extend and hold their arms above their head for a long duration. Also, more exams become available, such as whole-body procedures for taller patients and gurney scans for larger patients.

Just like the transition from analog to digital technology in other industries, the technology required to create a digital image is lighter, and more compact, with looser constraints on system design. Using registered collimation, Discovery NM/CT 670 CZT contains detected events entirely within a single pixel aligned to one collimator hole, even at the outermost edges of the FOV. This reduction in dead space enables a system design that can get closer to anatomies and increase patient comfort.

THE BEST ANGLE FOR YOU AND YOUR PATIENT

The applications you use to interpret and communicate molecular information are just as important as the tracers used to highlight that information and the technology used to capture it.

Quantitative applications allow you to prove what you see and, more importantly, prove what can't be seen. They give you the assurance to determine the best course of treatment and the confidence to adapt treatment. They also give you the information to build a database of accurate results. Results that can be used to better inform the decisions you make for each patient and also, to inform the research that will develop more specific indications for disease.

Xeleris is our proven workstation dedicated to nuclear medicine. In the past, Xeleris led the way with mobilized applications that gave you accessible, easy-to-use tools to enhance productivity. Now, our latest version of Xeleris is leading the way with modern, quantitative applications for nuclear medicine; applications that help give you greater confidence of absolute quantitation in customizable, easy-to-read reports across multiple care areas.

A NEW ERA IN NUCLEAR MEDICINE

It takes a thoughtful mind to go in search of true discovery — a mind like yours that looks to establish new standards of care to have a lasting impact on the world around them. We appreciate your efforts to influence the future of medicine to benefits us all.

To help, we have worked with many of you to understand what obstacles stand in your way and what situations you seek. The result of our partnerships is Discovery NM/CT 670 CZT. We hope you see it as we do, as much more than another imaging product. We see it as a tool to help you to bring your theories to life.

¹In clinical practice, the use of Discovery NM/CT 670 CZT may improve lesion detectability depending on the clinical task, patient size, anatomical location and clinical practice. A consultation with a radiologist and a physicist should be made to determine the appropriate dose or scan time to obtain diagnostic image quality for the particular clinical task.

²Together with Clarity 2D and Evolution⁷ and compared to Discovery NM/CT 670 Pro/ES/DR without Clarity 2D and Evolution⁷. As demonstrated in phantom testing using NEMA IEC Body Phantom.

³Together with Clarity 2D & Evolution⁷. Compared to typical 15 minute scan on Discovery NM/CT 670 Pro/ES/DR without Clarity 2D & Evolution⁷.

⁴Demonstrated in phantom testing using NEMA IEC Body Phantom at 50% scan times with Evolution⁷. Compared to Discovery NM/CT 670 Pro/ES/DR.

⁵In clinical practice, the use of ASiR may reduce CT patient dose depending on the clinical task, patient size, anatomical location and clinical practice. A consultation with a radiologist and a physicist should be made to determine the appropriate dose to obtain diagnostic image quality for the particular clinical task.

⁶In clinical practice, the use of Discovery NM/CT 670 CZT may improve quantitation of lesions larger than 5.5mL, depending on the clinical task, patient size, anatomical location and clinical practice. A consultation with a radiologist and a physicist should be made to determine the appropriate dose or scan time to obtain the claimed quantitation accuracy for the particular clinical task.

⁷In clinical practice, Evolution options^7a (Evolution for Bone, Evolution for Cardiac, Evolution for Bone Planar) and Evolution Toolkit^7b are recommended for use following consultation of a Nuclear Medicine physician, physicist and/or application specialist to determine the appropriate dose or scan time reduction to obtain diagnostic image quality for a particular clinical task, depending on the protocol adopted by the clinical site.

^7aEvolution Options – Evolution claims are supported by simulation of count statistics using default factory protocols and imaging of 99mTc based radiotracers with LEHR collimator on anthropomorphic phantom or realistic NCAT – SIMSET phantom followed by quantitative and qualitative images comparison.

^7bEvolution Toolkit – Evolution Toolkit claims are supported by simulation of full count statistics using lesion simulation phantom images based on various radiotracers and collimators and by showing that SPECT image quality reconstructed with Evolution Toolkit provide equivalent clinical information but have better signal-to-noise, contrast, and lesion resolution compare to the images reconstructed with FBP/OSEM.